PBSI trial

Permanent Breast Seed Implant (PBSI) is a form of internal radiation therapy that involves radioactive seeds (Palladium-103) being percutaneously implanted in the cavity. This form of radiation is proven to be just as effective as standard external radiation therapy and significantly reduces the duration of radiation therapy: only one follow-up treatment is needed after the first treatment. PBSI is not yet administered in Europe. However, it was introduced as a new treatment in the Erasmus MC hospital in collaboration with Franciscus Gasthuis and Vlietland by our research team in August 2017. The most common side effects of PBSI are skin-related: they have a negative impact on cosmetics and quality of life. This research aims to examine and evaluate the effect of a subcutaneous injection with liquid on skin damage after PBSI.

Palladium-seed on finger. Source: BOR Foundation

Implantation of the seeds led by ultrasound. Source BreastMicroseed inc.

All seeds are implanted and will radiate locally for three months. Source: BreastMicroseed inc.

All seeds are implanted and will radiate locally for three months. Source: BreastMicroseed inc.

Palladium seeds in a breast shown on a mammogram. Source: BreastMicroseed inc.

 

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